Monday, November 2, 2009

More Fetal Echo Reference Values

Seems like I spent most of the month of October thinking about fetal echos in one form or another. Apart from the earlier release of the Fetal Echo Z-Scores: Femur Length calculator, I also developed a couple of "helper" routines:

  • A calculator to cross-check the femur length against the EGA derived from dates. Also Gives reference values for fetal thoracic circumference:

    Fetal Biometry

  • A remake of the CHOP calculator- useful for describing the hemodynamic status of the recipient twin in twin-twin transfusion syndrome (TTTS). Good stuff for reminding me about the various manners in which heart failure can be categorized by fetal echo:

    CHOP Fetal CV Profile Score

  • A calculator for fetal LV/RV/IVS wall thicknesses. In the absence of any published z-score equations, these two sources (one uses autopsy data) seem to be our only recourse:

    Fetal Ventricular Wall Thickness Reference Values


Additionally, the October 13 issue of Circulation brought a new fetal echo z-score reference:

Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndrome.
McElhinney DB, Marshall AC, Wilkins-Haug LE, Brown DW, Benson CB, Silva V, Marx GR, Mizrahi-Arnaud A, Lock JE, Tworetzky W.
Circulation. 2009
Oct 13;120(15):1482-90. Epub 2009 Sep 28.

I won't attempt an analysis beyond the smackdown itself because, as the authors reveal, these new z-score equations are based on

unpublished fetal norms…

Still, it is interesting (to me) to see the data published at all, and I think the smackdown sheds some interesting light on the two groups of equations.

fetal_aov_plot