Friday, October 3, 2008

Aortic Stenosis: Discriminant Score

Based on work from Boston Children's Hospital, this calculator determines the aortic valve z-score and the discriminant score — for "predicting which neonates with AS are suitable for biventricular repair and which are better served by single ventricle management."

Discriminant Score Calculator

 
Results
   
 

Analysis:

"If EFE is omitted from the analysis (owing to high interobserver variability in grading), the most accurate model for predicting survival with a biventricular circulation is: 12.16 (BSA) + 0.59 (aortic valve annulus z-score) + 5.73 (LAR) - 7.02 with a discriminant cutoff of -0.46 accurately predicting 91% of survivors and 80% of events (87% overall)."

References:

Validation and Re-Evaluation of a Discriminant Model Predicting Anatomic Suitability for Biventricular Repair in Neonates With Aortic Stenosis
Steven D. Colan, MD*, Doff B. McElhinney, MD, Elizabeth C. Crawford, RDCS, John F. Keane, MD and James E. Lock, MD
J Am Coll Cardiol, 2006; 47:1858-1865, doi:10.1016/j.jacc.2006.02.020 (Published online 11 April 2006).

 

(Since I dropped this calculator from the ParameterZ.com remodel, I had to find a new home for it... here.)